Title
Uticaj surfaktanata na protolitičke ravnoteže i izomeraciju ACE inhibitora
Creator
Popović, Marija R., 1984-
Copyright date
2015
Object Links
Select license
Autorstvo-Nekomercijalno-Bez prerade 3.0 Srbija (CC BY-NC-ND 3.0)
License description
Dozvoljavate samo preuzimanje i distribuciju dela, ako/dok se pravilno naznačava ime autora, bez ikakvih promena dela i bez prava komercijalnog korišćenja dela. Ova licenca je najstroža CC licenca. Osnovni opis Licence: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/deed.sr_LATN. Sadržaj ugovora u celini: http://creativecommons.org/licenses/by-nc-nd/3.0/rs/legalcode.sr-Latn
Language
Serbian
Cobiss-ID
Theses Type
Doktorska disertacija
description
Datum odbrane: 03.09.2015.
Other responsibilities
mentor
Popović, Gordana, 1957-
mentor
Agbaba, Danica, 1953-
član komisije
Nikolić, Katarina, 1975-
član komisije
Tešić, Živoslav, 1953-
član komisije
Filipić, Slavica, 1980-
Academic Expertise
Medicinske nauke
University
Univerzitet u Beogradu
Faculty
Farmaceutski fakultet
Alternative title
The effect of surfactants on protolytic equlibria and isomerization of ACE inhibitors
Publisher
[ M. R. Popović]
Format
156 listova
description
Farmacija - Farmaceutska-medicinska hemija i strukturna analiza / Pharmacy / Pharamaceutical-medical chemistry and structural analysis
Abstract (sr)
U ovoj doktorskoj disertaciji ispitane su protolitičke ravnoteže i ravnoteža(Z)/(E)- izomerizacije devet ACE inhibitora (kaptopril, cilazapril, fosinopril, lizinopril, perindopril, ramipril, kvinapril, zofenopril) u micelarnim rastvorima surfaktanata različitog naelektrisanja, anjonskog (natrijum-dodecilsulfat, SDS), katjonskig (cetiltrimetilamonijum-bromid, CTAB)i nejonskog (4-oktilfenolpolietoksilat, TX 100)...
Abstract (en)
In this doctoral dissertation the protolytic equilibria and the (Z)/(E)equilibria of nine ACE inhibitors (captopril, cilazapril, fosinopril, lisinopril, perindopril, ramipril, quinapril and zofenopril) were investigated in micellar solutions of differently charged surfactants, anionic (sodium-dodecyl - SDS), cationic (cetyltrimethyilammonium-bromide, CTAB)and nonionic (4-octylphenol polyetoxylate, TX 100)...
Authors Key words
ACE inhibitori, surfaktanti, (Z)/(E)- diasteroizomerija, Hyperguad, RP-HPLC, DFT
Authors Key words
ACE inhibitors, protolytic equilibria, (Z)/(E)diasteroisomerism, surfactants, Hyperguad, RP-HPLC, DFT
Classification
615.225.011:543.395(043.3)
Type
Tekst
Abstract (sr)
U ovoj doktorskoj disertaciji ispitane su protolitičke ravnoteže i ravnoteža(Z)/(E)- izomerizacije devet ACE inhibitora (kaptopril, cilazapril, fosinopril, lizinopril, perindopril, ramipril, kvinapril, zofenopril) u micelarnim rastvorima surfaktanata različitog naelektrisanja, anjonskog (natrijum-dodecilsulfat, SDS), katjonskig (cetiltrimetilamonijum-bromid, CTAB)i nejonskog (4-oktilfenolpolietoksilat, TX 100)...
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